SNP Genotyping
SNP genotyping provides insights into genetic diversity, inheritance, and evolution, making it a versatile tool in genetics and genomics research.
Single Nucleotide Polymorphism (SNP) genotyping, is a genetic analytic method to identify single nucleotide variations in a target genome and is used in various research areas including the following:
- Traits and diseases
- Pharmacogenomics for personalized medicine
- Population genetics
- Ancestry tracing
- Forensics
- Agriculture and plant breeding
- Clinical diagnostics
- Phylogenetics
Unlock Precision in Your Research with ACGT’s SNP Genotyping Services
Discover the power of accurate genotyping with ACGT’s state-of-the-art technologies, including NGS, Sanger sequencing, TaqMan genotyping, and custom-designed assays. Whether your focus is on personalized medicine or evolutionary studies, our expert team ensures high throughput and unparalleled quality in every project.
Service Options
Short and Long Read NGS
ACGT’s short read or long read NGS technology can be used to evaluate SNP status of various DNA and RNA targets, from single PCR amplicons to whole genomes. Analysis can range from a single SNP of interest to thousands. Allele discrimination and haplotype phasing can be accomplished via bioinformatics tools for short read NGS, or directly via long read methods. The exceptional depth of coverage possible with short read NGS allows for variant frequency analysis of somatic tumor samples at as low as 1% frequency.
Sanger Sequencing
ACGT’s Sanger sequencing service can be used to economically evaluate SNP status of both DNA and RNA targets from many types of organisms, via PCR and RT-PCR amplicons. Analysis can range from a single to multiple SNPs of interest. Allele discrimination and haplotype phasing can be accomplished via bioinformatics tools.
MGB (TaqMan) Genotyping
TaqMan SNP Genotyping assays can help you detect and distinguish SNPs accurately and efficiently. Minor Groove Binder (MGB) technology enables TaqMan probes to discriminate between highly homologous allele sequences. We offer ABI QuantStudio 6 Flex Real-Time PCR System, which can be used for SNP genotyping utilizing over 17 million ThermoFisher Scientific SNP assays for human and mouse, including 4 million HapMap SNPs, nearly 1 million coding SNPs, and 1.4 million common 1000 Genomes SNPs.
Need analysis using a SNP Genotyping assay for a novel target?
We will help you design and validate it!
