CLINICAL CANCER PROFILING
ACGT has invested in the development of our oncology research support services to meet the needs of physicians and the medical community. A key feature of our cancer analysis strategy is the application of Next Generation Sequencing (NGS). The massively parallel sequencing technology of NGS enables a deep sequencing of tumor biopsies, fine needle aspirations (FNAs), or circulating tumor cells (CTCs). This allows for a detailed profiling of the cancer through identification of hundreds of mutations. As data sets accumulate with functional studies and patient outcomes, new cancer-related biomarkers may be identified and validated.
NGS Cancer Analysis Services
- Whole Genome Sequencing (WGS) of tumor genomes with NGS, including tumor vs. normal tissue comparative analysis
- Tumor vs. normal tissue exome analysis
- Cancer gene panel analysis (off the shelf panels from multiple providers, or custom panel development)
- Tumor RNA-Seq (transcriptome) analysis
- Tumor miRNA profiling
- Tumor methylome profiling
- ChIP-Seq analysis of user-provided enriched DNA samples
All clinical research support testing is offered at standard research or GLP levels, and is not intended or recommended for patient diagnosis or disease treatment decisions.
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Clinical NGS
Dr. Semyon Rubinchik, Scientific Director, addresses our NGS service as it applies to human patients, e.g. the sequencing of a tumor genome.